The Future of Formulation Development - Using Synchrotron Light

THE FUTURE OF FORMULATION DEVELOPMENT - USING SYNCHROTRON LIGHT                                                                             


PROFESSIONAL EDUCATION | LUND UNIVERSITY 

Synchrotron light has been used in the last decades to study formulations manufactured by the pharmaceutical, cosmetic and food industry. The use of synchrotron has allowed characterizing liquid and solid formulations, i.e. fingerprinting compounds and quantifying traces of polymorphs in a solid tablet formulation, and charaterizing variants in biopharmaceuticals. Moreover, the presence of last generation synchrotron facilities as MAX IV (Lund, Sweden) will definitely bring research in these areas beyond the limitations faced nowadays.                                                                    

AIM

This is the first in a series of courses with a goal to educate and enlarge the user base from industry and academia to utilize the potential of Big Science facilities such as MAX IV
and the interdisciplinary research at Lund University. Let experts from MAX IV, mediator companies and universities help you learn more about how you can perform an investigation in practice; from the first contract, to measurement, analysis and interpretation of results. 

The aim of the course is to answer the questions: "Is synchrotron light useful to get a better understanding of my formulation? If so, how should I perform an experiment if I am
not familiar with these methods?" Thus, this course will provide participants with the understanding of the key information obtained by using synchrotron light to better understand solid or liquid formulation.
 
Characterizing formulations using synchrotron light is somehow lika a puzzle consisting of different pieces, i.e. industrial users, locat contact at the synchrotron, sample preparations, measurement planning and date interpretation. In order to put these pieces together, the course will describe the ecosystem that surrounds MAX IV Laboratory, including the actors that are present to help industry to make the best use of such state-of-the-art large-scale infrastructure. Thus, contributions from two mediator companies will show how the different pieces of the puzzle are put together and how this benefits the industrial community within formulation science. For those who are interested there is a possibility to add an extra half-day - The Formulation Day - for individual meetings with scientists within chosen areas of interest.

COURSE OUTLINE

This is an intensive two-day course including hands-on, which will be held in english at MAX IV Laboratory. The course has a focus on the interaction between industry interested in obtaining an insight into characterization of formulations and last-generation synchrotrons as MAX IV. The course is a mix of lectures, including basic background information about methods and examples relevant to formulation science and a panel discussion.
 
A central activity of the course will be to perform hands-on experiments on state-of-the-art laboratory instrumentation, which will provide the participants with a practical experience on how to perform a scattering/diffraction experiment and which results can be obtained using such methods.In addition, the course will include a visit to the MAX IV Laboratory facility. The participants will thus have the opportunity to get an overview on how they can make use of and benefit from the synchrotron light within the field of formulation science. It also gives an opportunity for the participants to exchange experience with other attendants and lecturers as well as nurture and strengthen their network.
 
The course is intended to focus on the challenges that participants are facing today. Thus, the attendees will be asked to submit questions and their own problems prior to the start of the course, which will be highlightened during the course. The Formulation Day provides a further possibility for deeper discussions with experts. The Formulation Day will be tailored for each participants within the scope of the course.
 
To read the course description as well as the lecture plan, please click here.
 
Day 1  (@ Max IV):
  • Basics on scattering (light, X-rays and neutrons)
  • X-rays in formulation science
  • Examples of the use of SAXS in formulation science
  • Synchrotron X-ray Powder Diffraction (XRPD)
  • Visit to the MAX IV facility
       Course dinner

 

Day 2  (@ Kemicentrum):
  • Hands-on labs
  • Route from questions to results

 

LECTURERS

Björn Bergenståhl, professor in Food Technology at Lund University since 1998. For more than 15 years, he worked as researcher and section manager at YKI Institute for Surface Chemistry in Stockholm. He has a long-term experience in applied surface and colloid chemistry in industrial systems (chemical technical, paint, paper, mining, pharmaceutical and food industry) and on surface properties of solid systems obtained through drying. Another area of interest is the influence of the surface physics on the functional properties of industrial powders (wettability, dispersability and flowability).

 
Fabia Gozzo has more than 10 years of practical eexperience with synchrotron light from the Paul Scherrer Institute, where she has developed a state-of-the-art powder diffractometer. She is also head of the spin-off company Excelsus Structural Solutions in Swizerland. 

Fabia is recognized as a synchrotron- and powder diffraction expert, and has built a substantial industrial and academic user community, including some large pharmaceutical compani
 
 
 
 
 
Peter Schurtenberger is a professor in Physical Chemistry at Lund University. His research interests focus on soft matter, nanotechnology, biophysics, material sciences, on the characterization of soft matter with light, X-ray and neutron scattering, and on the development of new instruments for this task. 
 
In 2006 he founded the Fribourg Center for Nano-materials, and became the first director of the newly founded Adolphe Merkle Institute for Pure and Applied Nanoscience in 2008. He moved to Lund 2010. He has been elected as a member of the Royal Swedish Academy of Sciences, the Royal Swedish Academy of Engineering Sciences, is a Fellow of the Royal Society of Chemistry.
 
 
 
Other lecturers include Stefan Ulvenlund (CSO at CR Compentence AB and professor in Formulation technology at Lund Univeristy), Marc Obiols-Rabasa (scientist at CR Competence AB with 10 years of experience in characterization of soft nanomaterials using scattering methods such as light, X-rays and neutrons), Thomás Plivelic (Beamline manager at MAX IV) and Marjolein Thunnissen (Head User Office at MAX IV).
 

SCHEDULE, FEE & LOCATION

September 27-28, 2017
 
The course will take place at Lund University and MAX IV. The course fee is SEK 11 950, excluding VAT. The course fee includes tuition, documentation, diploma, coffee, lunch and a dinner on Day 1.
 
The course will be held from 8.30 am to 5 pm on all days.
 
Those who are interested can add The Formulation Day on September 29th held from 8.30 to 12.00 am for a fee. 
 
REGISTRATION DEADLINE
 
Registration deadline is August 31st, 2017. However registration is open until the course starts, provided that the course has not been filled. If the course is filled you will be automatically notified and placed as a reserve. Registration is binding. Substitution of participants is allowed at any time at no charge, however it is advisable that such should take place at the start of the course.

WHO SHOULD ATTEND?

This is a course combining science and applications of the use of synchrotron light within formulation science. Thus it's aimed at R&D Managers, industrial specialists and project leaders at companies, as well as university researchers, who want to learn how they can make use of and benefit from synchrotron light within formulation science.

 

CONTACT

For course information, please contact Mirka Fahlander at Lund University Commissioned Education,

Ph. +46-46-222 0777 or mirka.fahlander@education.lu.se

For practical information, please contact Andreas Bryngelson,
Ph. +46-46-222 1460 or andreas.bryngelson@education.lu.se
 
 

REGISTRATION

 

Lund University Commissioned Education (LUCE) is Lund University’s department for commissioned education and competence development for professionals. With the latest science as a base we develop and sell courses, programs and seminars in a close cooperation with organizations, companies and local, national and international authorities. Our educations is performed by teachers and scientists at Lund University – a guarantee for subject-related width, scientific depth and modern pedagogy. You’re welcome to contact us for more information! Phone 046-222 0707 or info@education.lu.se , Lund University Commissioned Education Box 117, 221 00 Lund.


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